Client:

The client is an international nonprofit organization, focusing on developing innovations and implementing solutions that save lives and improve health. The goal of this project was to provide a robust, user-friendly test used by organizations within Low and Middle-Income Countries (LMIC) to assess the micronutrient status of local, at-risk populations.

CHALLENGE

Situation:

At the time, the method used by the customer to determine the micronutritional state of a given population employed individual ELISA kits targeting five unique biomarkers. These included AGP, CRP, Ferritin, sTfR, and RBP-4. This process was very costly and required a great deal of time and sample to generate the required biomarker data to make informed decisions. The high resource burden associated with these current methods limited many LMICs in their ability to determine the prevalence of nutritional deficiencies within their populations, plan targeted nutritional interventions, and track the effects of such efforts.

Technical Need:

There was a need for a standardized platform that could save time, reduced costs and provide a quick and efficient way to analyze data. Additionally, this solution would allow for localized ability to process the tests and receive timely results which were key to the success of this study.

SOLUTION

Quansys Biosciences created a multiplex kit for simultaneous measurement of all five biomarkers. Coupled with the robust Q-View™ imaging system and user friendly Q-View™ Software, this multiplex solution not only significantly lowered the resource requirement of LMICs undertaking population surveys, but also allowed for in country data generation.

RESULTS

The Q-Plex™ Human Micronutrient array quantifies vitamin A and iron, biomarkers simultaneously using only 10μl of sample. This kit addresses the key logistical obstacles to population surveillance by minimizing the complexity and cost of specimen collection, sample preparation, and testing.

Recognized savings moving to Q-Plex™ kits from traditional ELISA testing

  • Kits: $108,000
  • Labor: 2850 hours per year
  • Sample: 100 μl/sample

Total: $251,000 per year