Client:

Simon Fraser University (SFU), is a public research university in British Columbia, Canada. SFU’s Biomedical Engineering faculty is involved in leading-edge research across a broad spectrum of disciplines including demographic and health surveys.

CHALLENGE

Situation:

SFU was actively researching the effects of psychosocial, energetic, and environmental, challenges on growth, development, reproduction, and health of women in Guatemala. Urine samples were being tested using clinical ELISAs for each biomarker. This process not only incurred the significant expenses of personnel time, tests, reagents, and consumables, but it also required larger sample quantities which increased the storage and transportation costs.

Technical Need:

SFU needed to find a way to reduce the cost of this research while at a minimum, maintaining the same level of performance in the data. It was their objective to minimize the required amount of sample, reducing storage and shipping costs. They also wanted to streamline the testing process, cutting the expenses involved with running individual traditional ELISA immunoassays.

SOLUTION

Quansys Biosciences organized all of the biomarkers currently being tested by SFU into a single multiplex array. This Female Hormone kit, successfully combines both sandwich ELISAs and competitive assays into a single well of a 96 well plate, while maintaining, and in some cases improving, individual biomarker sensitivity and reproducibility. Acquiring the data from six unique analytes could now be accomplished from a single dilution in a multiplex test.

RESULTS

“Measuring multiple hormones simultaneously in a single assay saves sample volume, labor, time, reagents, money and consumables. Thus, multiplex arrays represent a faster, more economically and ecologically sound alternative to singleton assays.”1

“This multiplex technology provides a more economical, rapid, and ecologically sound alternative to individual assays for studies requiring the measurement of multiple biomarkers per biospecimen.”2

Savings Moving to Q-Plex™

  • Kits: $69,440
  • Labor: 1250 hours per year
  • Sample: 125 μl/sample

Total: $131,000 per year

1 Am J Hum Biol. 2012 Jan-Feb;24(1):81-6. doi: 10.1002/ajhb.21229. Epub 2011 Nov 28.
2 Ibid.