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Mouse Cytokine Screen – IR (16 Plex) |
Product Information Sheet (PDF) MSDS Information |
Catalog #130951MS
The Q-Plex™ Mouse Cytokine – IR (16-plex) is a fully quantitative ELISA-based test where 16 distinct capture antibodies have been absorbed to each well of a 96-well plate in a defined array. Using less than 30 µl of sample per well, up to 80 samples can be assayed for all 16 markers in less than 5 hours. The Q-Plex™ Mouse Cytokine – IR (16-plex) provides researchers an easy to use and cost effective means of generating a cytokine profile for each sample. The array is analyzed using the LI-COR Odyssey and Aerius Infrared Imagine Systems.
Many cytokines perform multiple functions and often share the same receptors. A single cytokine can elicit many different effects dependent on the cell type and the other cytokines present. This diversity of activity is what allows the immune system to control a great variety of events with a relatively small repertoire of signaling agents. As a result, the profile of type and concentration of cytokines present at a specific time is critical to receiving the desired function. Because these profiles define what is happening in the immune system, and because of cytokine involvement in both disease pathogenesis and disease recovery, the monitoring of their levels is an invaluable tool in understanding, diagnosing, and monitoring disease.
| Range (pg/ml) |
LLD (pg/ml) | Standard* (pg/ml) |
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|---|---|---|---|
| IL-1α | 5300 – 7 | 0.44 | 5300 |
| IL-1β | 26000 – 36 | 4.14 | 26000 |
| IL-2 | 5500 – 8 | 2.59 | 5500 |
| IL-3 | 5500 – 8 | 0.47 | 5500 |
| IL-4 | 6300 – 9 | 0.79 | 6300 |
| IL-5 | 8400 – 12 | 1.94 | 8400 |
| IL-6 | 4600 – 6 | 0.11 | 4600 |
| IL-10 | 2600 – 4 | 0.43 | 2600 |
| IL-12 | 9000 – 12 | 0.60 | 9000 |
| IL-17 | 15000 – 21 | 2.96 | 15000 |
| MCP-1 | 13000 – 18 | 5.08 | 13000 |
| IFNγ | 13000 – 18 | 0.43 | 13000 |
| TNFα | 6000 – 8 | 0.05 | 6000 |
| MIP-1α | 8700 – 12 | 3.89 | 8700 |
| GMCSF | 5800 – 8 | 0.77 | 5800 |
| RANTES | 13000 – 18 | 0.66 | 13000 |
| *The concentration of the Antigen Standard when reconstituted with 300 µl. This will be the concentration of the high point of the standard curve. |
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