Catalog Number: 140251MS Price: $900 Product Information Sheet MSDS Information

Chemokines are a generic class of pro-inflammatory cytokines which promote chemotaxis. Secreted by numerous cell types, these proteins are usually induced by cell damage as a result of infection. They can also be secreted in other pathologies (e.g. cancer), or be used in normal events such as hematopoiesis and angiogenesis. Chemokines are specific in the types of cells they attract, though each chemokine can activate multiple receptors and a single receptor can bind multiple chemokines.

Chemokine profiling is a particularly valuable tool. Expression is a great indicator of a system out of homeostasis, while the profile is indicative of the types of cells involved in the immune's system's response. These profiles also provide clues to other events like angiogenesis and hematopoiesis.

	Range (pg/ml)	LLD (pg/ml)	Standard* (pg/ml)
Eotaxin	2600 - 3.57	2.91	2600
IP-10	20600	28.26	20600
KC	8700 - 11.93	2.51	8700
MCP-1	3500 - 4.80	2.25	3500
MDC	11000 - 15.09	2.29	11000
MIP-1α	7500 - 10.29	1.03	7500
RANTES	6500 - 8.92	0.81	6500
TARC	10000 - 13.72	14.51	10000
TCA-3	4700 - 6.45	2.52	4700
*The concentration of the Antigen Standard when reconstituted with 300 µl. This will be the concentration of the high point of the standard curve.

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