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Immunoglobulins are multimeric glycoproteins secreted by plasma cells and regulated by the humoral immune system. They have a central role in acquired immunity in vivo, but have been utilized in vitro for various applications including Immunoassays. The development of hybridoma technology has particularly expanded this latter use. Quansys Biosciences' Mouse Immunoglobulin array was specifically designed for antibody developers to use in monitoring antibody titers during immunization and characterizing the developed hybridomas.

The mouse immunoglobulin array is a rapid (20 minutes), fully quantitative assay used to simultaneously quantitate 6 antibody isotypes as well as the ratio of kappa to lambda light chains. Its multiple uses include rapid and efficient characterization of monoclonal antibody producing hybridomas; immunological monitoring of mice prior to fusion; and as a screen in mouse model studies of human diseases known to affect antibody concentrations and ratios.

	Range (pg/ml)	LLD (pg/ml)	Standard* (pg/ml)
IgG1	480 - 30	2.2	480
IgG2a	518 - 32	1.7	518
IgG2b	593 - 37	3.0	593
IgG3	265 - 17	7.5	265
IgA	1178 - 74	1.8	1178
IgM	73 - 5	0.4	73
Kappa	N/A	N/A	N/A
Lambda	N/A	N/A	N/A
*The concentration of the Antigen Standard when reconstituted with 300 µl. This will be the concentration of the high point of the standard curve.

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