Mouse IL-3 Analyte Overview
Also known as IL-3, Interleukin 3, Hematopoietic growth factor, mast-cell growth factor
Interleukin 3 (IL-3) is a cytokine that promotes immune responses. It is produced by basophils and activated T cells to stimulate the proliferation and differentiation of multipotent hematopoietic stem cells as well as lineage committed progenitor cells. Due its numerous functions and targets, it has been studied under different names, including mast cell growth factor, P-cell stimulating factor, burst promoting activity, multi-colony stimulating factor, thy-1 inducing factor and WEHI-3 growth factor. The behavior of many immunological cells is impacted by IL-3 activity, including mast cells, basophils, eosinphils, and macrophages. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils and various myeloid leukemic cells and the cytokine influences many cell activities, including growth and apoptosis. IL-3 has neurotropic effects and may be involved in some neurological disorders.
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