PF-4

Analyte Overview

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PF-4

Name(s): PF-4, Platelet Factor 4, Chemokine Ligand 4, CXCL4

Ranges: 

        Human: 65000-89.16 pg/ml

Species: Human

Sample Type: Serum, Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available

 

Analyte Description

Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine that plays a role in wound response and repair. When a blood clot is forming, PF4 is released from active platelets during aggregation and contributes to blood coagulation by regulating heparin-like molecules. It is also chemotactic to many other types of immune cells and inhibits the blood vessel formation, blood cell differentiation, and the activity of T cells. Dysregulation of PF4 and heparin or can lead to thrombosis. PF4 is critical during infection with malaria, as it controls the parasite by lysing its digestive vacuole.

Q-Plex™ Products featuring PF-4

Human Multiplex Kits

Current retail kits unavailable, contact an Account Executive for custom printing.

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