Human C-Peptide Analyte Overview
Also known as C-Peptide, Connecting Peptide
C-Peptide is a short polypeptide responsible for connecting insulin’s A-chain to its B-chain to form the proinsulin molecule. In addition to its critical role in insulin processing, the peptide influences microvascular blood flow and tissue health, where it has anti-inflammatory effects and aids in the repair of smooth muscle. The body produces insulin and C-peptide in equal amounts, so when a patient is receiving insulin injections, C-peptide may be measured to determine how much natural insulin they are producing on their own. Clinically, C-peptide is often measured to distinguish between type 1 and type 2 diabetes, provide differential diagnosis of hypoglycemia, evaluate degree of insulin resistance in women with polycystic ovarian syndrome (PCOS), and evaluate the risk of additional abnormal growths in patients with Multiple Endocrine Neoplasm syndromes (MEN).
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