Human hCGβ Analyte Overview
Also known as HCG beta, Human Chorionic Gonadotropin beta sub-unit, HCG
Human Chorionic Gonadotropin Beta Subunit (hCGβ) is a glycoprotein hormone that acts as an autocrine factor during early pregnancy to support the development of a zygote into an embryo. Its primary role is to establish a pregnancy in the uterus lining and regulate the growth and function of the placenta. hCGβ also works to prevent an immune response to the growing embryo by suppressing immune activity in the uterus. The complete hCG is composed of an alpha unit shared by numerous reproductive hormones and the beta unit, hCGβ, which is unique to hCG. hCGβ is a common target for pregnancy tests, some cancer diagnostics, and in professional athlete testing. HCGβ is often produced by ovarian and testicular germ cell tumors and advanced cancers that have dedifferentiated and is often used as a tumor marker. hCG is commonly used as part of a performance enhancing drug treatment cycle to restore normal testosterone levels and is commonly one of the substances tested for in athletics.
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