Human IL-18BP Analyte Overview

Human IL-18BPα

Also known as IL-18 binding protein

Interleukin 18 binding protein (IL-18BPa) is an endogenous soluble factor that specifically inhibits the action of IL-18. IL-18BPa is constitutively expressed by mononuclear cells and is detectable in the serum of healthy humans at a high ratio to IL-18, suggesting that IL-18 concentration must overcome a threshold. However, mice with IL-18BPa deficiency mice have decreased levels of IL-18 in their blood, suggesting that IL-18BPa may also function as a carrier to maintain concentration of IL-18.

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Features & Requirements

  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

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