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Human IL-1Rα Analyte Overview

Human IL-1Rα

Also known as IL-1R alpha, IL-1F3, Interleukin-1 Receptor Antagonist

Interleukin 1 receptor antagonist (IL-1Ra) is an acute phase protein that is a member of the Interleukin 1 family of cytokines. It blocks Interleukin 1 alpha and beta (IL-1α and IL-1β) from binding to the Interleukin 1 receptor type 1. The IL-1 family plays an important role in both adaptive and innate immunity through promoting inflammation, IL-1Ra works to reduce inflammation and fever responses. It is secreted by a variety of cell types, including immune cells, epithelial cells, and adipocytes. It is commonly used in veterinary medicine to calm inflamed soft tissue injuries. A modified version is used in human medicine to treat rheumatoid arthritis. Aberrations in IL-1Ra are associated with schizophrenia and are commonly found in high levels in schizophrenia patients.

Q-Plex™ Details

Species: Human
Assay Type: Sandwich
Sample Type: Human Serum, EDTA Plasma
Assay Range: 1,100 – 1.51 pg/mL
Lower Limit of Detection (LLD): 0.05 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Catalog #: 

Features & Requirements

  • Measure IL-1Rα in 2.25 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

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