fbpx

Human MMP-2 Analyte Overview

Human MMP-2

Also known as MMP-2, MMP2, MMPII, TBE-1, Matrix Metalloproteinase-2, 72 kDa type IV Collagenase, Gelatinase A, CLG4, CLG4A, MONA

Matrix metalloproteinase 2 (MMP2), also known as gelatinase A, is an enzyme capable of breaking down type IV collagen. It is a member of the MMP family, a group of structural related zinc-dependent endopeptidases that are involved in breaking down different components of tissue. MMP2 degrades basement membranes made of type IV collagen, particularly during the menstrual cycle and early embryonic development. Overactivity of MMP2 is associated with severe chronic airway diseases, particularly pneumonia and bronchiectasis. Elevated MMP2 is associated with many types of cancer, where it’s effects on tumor progression are well documented – it supports tumor invasion into tissue, alters cell signaling to dampen immune response to the tumor, and promotes tumor blood vessel formation. Given MMP2’s role in multiple aspects of cancer biology, it is under investigation as a potential target for cancer medications.

Q-Plex™ Details

Species: Human
Sample Type: Human Serum, EDTA Plasma
Assay Range: 80,000 – 329.22 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate

Features & Requirements

  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

Featured Q-Plex Products

Human Multiplex Kits

Not Finding What You Need?

Customize a Kit

Not seeing the biomarker or analyte you need? Customize your kit! The Q-Plex™ Custom Assays are fully quantitative ELISA-based Chemiluminescent assay kits allowing the concurrent measurement of up to 18 biomarkers or analytes.

Send in Your Samples

Choose up to 18 different biomarkers that will work best for your research. Send in your samples and let us run them for you. 

Contact a Representative

Have questions about the kit or interested in more information? Contact one of our representative to get all your questions answered. 

As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.