Mouse GMCSF Analyte Overview


Also known as granulocyte macrophage colony stimulating factor,  GM-CSF, colony-stimulating factor 2, CSF 2

Granulocyte-macrophage colony-stimulating factor (GM‑CSF), also known as colony-stimulating factor 2 (CSF2), is a growth factor that promotes the formation of white blood cells and is a critical component of the immune/inflammatory cascade. The growth factor is commonly used for in vitro colony formation of white blood cells. Numerous cell types produce GM-CSF in response to inflammation, particularly in the immune system, including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes. In hematopoietic cells, GM-CSF activates the functions of monocytes, macrophages, eosinophils, and granulocytes. In clinical settings, GM-CSF is capable of raising white blood cell counts in chemotherapy and bone marrow transplant patients and is being investigated as a potential cancer vaccination due to its ability to transfer targeted genetic material into tumor cells. Since GM-CSF initiates the development of an immune response, it is implicated in autoimmunity disorders and allergic inflammation. Patients with rheumatoid arthritis often have high levels of GM-CSF in their joints.

Q-Plex™ Details

Species: Mouse
Assay Type: Sandwich
Sample Type: Serum
Assay Range: 560 – 0.77 pg/mL
Lower Limit of Detection (LLD): 0.38 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate

Features & Requirements

  • Measure GMCSF in 2.25 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

Featured Q-Plex Products

Q-Plex™ Mouse Cytokine Inflammation HS (13-Plex)

GMCSF, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-6, IL-10, IL-12p70, IL-17A, MIP-1α, RANTES, TNFα

Q-Plex™ Mouse Cytokine Screen HS (15-Plex)

GMCSF, IFNγ, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-17A, MIP-1α, RANTES, TNFα

Q-Plex™ Mouse Cytokine Screen HS Stripwells(15-Plex)

GMCSF, IFNγ, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-17A, MIP-1α, RANTES, TNFα

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