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Human MPO Analyte Overview

Human MPO

Also known as MPO, Myeloperpxidase

Myeloperoxidase (MPO) is a peroxidase enzyme produced primarily by granulocytes within neutrophils. It creates a powerful oxidant, hypochlorous acid, that has bactericidal and viricidal abilities and gives neutrophils their antimicrobial properties. MPO is stored in azurophilic granules and released during degranulation. When the body forms antibodies against MPO, it can lead to destruction of blood vessel walls in many kinds of vasculitis. MPO is implicated in cardiac diseases, elevated levels are particularly associated with coronary artery disease. MPO may also contribute to the atherosclerosis by promoting endothelial dysfunction. MPO staining is frequently used in the diagnosis of myeloid sarcoma. MPO is commonly used to predict myocardial infractions in patients with chest pain.

Q-Plex™ Details

Species: Human
Sample Type: Human Serum, EDTA Plasma
Assay Range: 1,560 – 2.14 ng/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate

Features & Requirements

  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

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