NHP IL-12p40 Analyte Overview
Also known as IL-12 p40, Interleukin-12 subunit beta, IL-12B, Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor p40, Inactive Homodymer of interleukin-12
Interleukin 12 p40 (IL-12 p40) is a subunit of interleukin 12 (IL-12) a cytokine that has a broad range of biological activities in the immune system. The complete IL-12 unit aids in the differentiation of naïve T cells into Th1 cells and regulates the activity of natural killer cells. It also stimulates the production of T cells, IFN-γ, and TNF-α. IL-12 inhibits the formation of new blood vessels and may play a role in autoimmune disorders. Overexpression of IL-12 p40 is associated with multiple sclerosis. IL-12 p40 is also a subunit of Interleukin 23.
Typical Assay Characteristics
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