NHP IL-6R Analyte Overview


Also known as gp80, CD 126, IL6RQ, IL6Q, Interleukin-6 Receptor, Cluster of Differentiation 126 (CD126)

Interleukin 6 receptor (IL6R), also known as CD126, is a functional receptor for the IL-6 cytokine, that regulates many activities in the immune system, muscle tissue, and bone tissue. The receptor is commonly is expressed on hepatocytes, neutrophils, monocytes, B cells, and T cells, and in organs including muscle tissue, the heart, kidney, liver, spleen. placenta, lung, and brain. IL-6 and IL-6R have a low affinity for one another. High levels of IL-6R are often found in patients with early stage rheumatoid arthritis. Abnormal behavior of IL-6 and/or IL-6R is associated with chronic inflammatory conditions such as Crohn’s disease, multiple myeloma, and ulcerative colitis, as well as many cancers.

Q-Plex™ Details

Species: NHP
Assay Type: Sandwich
Sample Type: Serum/Plasma, Cell Supernatant
Assay Range: 1,250 – 171 pg/mL
Lower Limit of Detection (LLD): 0.86 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate

Features & Requirements

  • Data available as fast as 4 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis of multiplexed chemiluminescent planar-based arrays

Featured Q-Plex Products

Q-Plex™ NHP Anti-Inflammatory Panel 1 (7-Plex)

IL-1RA, IL-2Rα, IL-4, sIL-6R, IL-10, IL-13, TNFRII

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