NHP TNFRII Analyte Overview


Also known as Tumor Necrosis Factor Receptor II

Tumor necrosis factors (TNFs) are a pleiotropic group of inflammatory cytokines crucial in how the immune system responds to injury or infection. Two forms of TNF exist, TNFα and TNFβ which compete for binding to the same receptors. Two different receptors have been described, tumor necrosis factor receptor (TNFR) I and TNFRII. The receptors are immunologically distinct and show high affinity binding to either TNFα or TNFβ. Soluble forms of the TNFRs have been described in human serum and urine which can neutralize the biological activity of TNFs though the physiological role of soluble TNFRs is not completely understood.

Q-Plex™ Details

Species: NHP
Assay Type: Sandwich
Sample Type: Serum/Plasma, Cell Supernatant
Assay Range: 2,000 – 2.74 pg/mL
Lower Limit of Detection (LLD): 1.37 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate

Features & Requirements

  • Data available as fast as 4 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis of multiplexed chemiluminescent planar-based arrays

Featured Q-Plex Products

Q-Plex™ NHP Anti-Inflammatory Panel 1 (7-Plex)

IL-1RA, IL-2Rα, IL-4, sIL-6R, IL-10, IL-13, TNFRII

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Not seeing the biomarker or analyte you need? Customize your kit! The Q-Plex™ Custom Assays are fully quantitative ELISA-based Chemiluminescent assay kits allowing the concurrent measurement of up to 18 biomarkers or analytes.

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