Human TGFβ Analyte Overview

Human TGFβ

Also known as TGFβ1, Transforming Growth Factor Beta

Transforming growth factor beta (TGF-β) is a cytokine with numerous functions in the immune system. It is primarily secreted by macrophages in a latent form and activated by cellular signals of inflammation. TGF-β has many roles in the immune system, including enabling the differentiation of T cells, inhibiting B lymphocyte proliferation, stimulating monocytes, reducing macrophage activity, and regulating the cell cycle of local cells. TGF-β is a component of human breastmilk and is believed to support immune system development in infants. Abnormal expression of TGF-β is implicated in cancer when the cell cycle regulation of the cytokine is corrupted. The TGF-β signaling pathways associated with metabolism are often disrupted in obesity and diabetes. Reduced levels of TGF-β are seen in patients with multiple sclerosis. Disruptions in TGF-β signaling pathways are associated with Marfan syndrome, Loeys-Dietz syndrome, and Alzheimer’s disease. Elevated TGF-β is to blame for wrinkle formation, as it decreases subcutaneous fat in aging people.

Order the Q-Plex™ Human TGFβ HDR (6-Plex)

Please contact an Account Manager to order the kit. 

Q-Plex™ Details

Species: Human
Sample Type: Human Serum, EDTA Plasma
Assay Range: 31,000 – 1.984 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate

Features & Requirements

  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis

Not Finding What You Need?

Customize a Kit

Not seeing the biomarker or analyte you need? Customize your kit! The Q-Plex™ Custom Assays are fully quantitative ELISA-based Chemiluminescent assay kits allowing the concurrent measurement of up to 18 biomarkers or analytes.

Send in Your Samples

Choose up to 18 different biomarkers that will work best for your research. Send in your samples and let us run them for you. 

Contact a Representative

Have questions about the kit or interested in more information? Contact one of our representative to get all your questions answered. 

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