Analyte Overview


MPO Overview

Name(s): MPO, Myeloperoxidase

Ranges: 1560-2.14 ng/ml

Species: Human

Sample Type: Serum, Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available


Analyte Description

Myeloperoxidase (MPO) is a peroxidase enzyme produced primarily by granulocytes within neutrophils. It creates a powerful oxidant, hypochlorous acid, that has bactericidal and viricidal abilities and gives neutrophils their antimicrobial properties. MPO is stored in azurophilic granules and released during degranulation. When the body forms antibodies against MPO, it can lead to destruction of blood vessel walls in many kinds of vasculitis. MPO is implicated in cardiac diseases, elevated levels are particularly associated with coronary artery disease. MPO may also contribute to the atherosclerosis by promoting endothelial dysfunction. MPO staining is frequently used in the diagnosis of myeloid sarcoma. MPO is commonly used to predict myocardial infractions in patients with chest pain.

Q-Plex™ Products featuring MPO

Human Multiplex Kits

Current retail kits unavailable, contact an Account Manager for custom printing.

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