Human GMCSF Analyte Overview

Human GMCSF

Also known as granulocyte macrophage colony stimulating factor,  GM-CSF, colony-stimulating factor 2, CSF 2

Granulocyte-macrophage colony-stimulating factor (GM‑CSF), also known as colony-stimulating factor 2 (CSF2), is a growth factor that promotes the formation of white blood cells and is a critical component of the immune/inflammatory cascade. The growth factor is commonly used for in vitro colony formation of white blood cells. Numerous cell types produce GM-CSF in response to inflammation, particularly in the immune system, including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes. In hematopoietic cells, GM-CSF activates the functions of monocytes, macrophages, eosinophils, and granulocytes. In clinical settings, GM-CSF is capable of raising white blood cell counts in chemotherapy and bone marrow transplant patients and is being investigated as a potential cancer vaccination due to its ability to transfer targeted genetic material into tumor cells. Since GM-CSF initiates the development of an immune response, it is implicated in autoimmunity disorders and allergic inflammation. Patients with rheumatoid arthritis often have high levels of GM-CSF in their joints.

GMCSF Q-Plex™ details

Species: Human
Assay Type: Sandwich
Sample Type: Serum, EDTA Plasma
Assay Range: 6,000 – 6.56 pg/ml
Lower Limit of Detection (LLD): 6.56 pg/ml
Volume Required Per Well: Min 25µl
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Catalog No: 464149HU

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Measure GMCSF in 2.25 hours

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Sensitive, reproducible, and convenient 96-well format requiring low sample volumes

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Requires the Q-View™ Imaging System for analysis

Q-Plex Multiplexed Products featuring GMCSF

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