Analyte Overview


IL-27 Overview

Name(s): IL-27, Interleukin 27


      Human: 67000-91.91 pg/ml

Species: Human

Sample Type: Serum, EDTA Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available


Analyte Description

Interleukin 27 (IL-27) is a member of the IL-12 cytokine family with both pro- and anti-inflammatory properties. It is expressed by antigen presenting cells and only interacts with the specific cell-surface receptor IL-27R. Its pro-inflammatory activity is driving the differentiation of T cells into active populations. However, it also mediates inflammation by suppressing Th17 and regulating the behavior of other T cells. It induces differentiation of the diverse populations of T cells in the immune system and upregulates anti-inflammatory IL-10. IL-27 appears to reduce the symptoms of many inflammatory and autoimmune diseases, particularly those driven by excess Th17, and is a target for therapeutic research. Low levels of IL-27 are associated with more severe cases of multiple sclerosis.

Q-Plex™ Products featuring IL-27

Human Multiplex Kits

Current retail kits unavailable, contact an Account Manager for custom printing.

As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.



365 North 600 West Logan, UT 84321