MMP 13

Analyte Overview


MMP 13 Overview

Name(s): MMP 13, matrix metallopeptidase 13, collagenase 3, CLG3, MANDP1, MDST


        Human: 35000-144.03 pg/ml

Species: Human

Sample Type: Serum, Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available

Analyte Description

Matrix metalloproteinase 13 (MMP13), also known as collagenase 3, is an enzyme that is involved with breaking down collagen. It is a member of the MMP family, a group of structural related zinc-dependent endopeptidases that are involved in breaking down different components of tissue. It is secreted by fibroblasts, chrondrocytes, and squamous epithelial cells as an inactive proprotein and is activated via processing with extracellular proteases. Though MMP13 is capable of breaking down collagen type I, II, and III, it is most efficient at degrading collagen type II. MMP13 is critical for normal bone formation during embryonic development, where it remodels the collagen matrix during mineralization. As with many members of the MMP family, high levels of MMP13 are associated with many kinds of cancer and arthritis. MMP13 is particularly implicated in osteoarthritis due to its role in cartilage remodeling. Aberrations in MMP13 expression are associated with developmental bone deformities.

Q-Plex™ Products featuring MMP 13

Human Multiplex Kits

As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.



365 North 600 West Logan, UT 84321