Analyte Overview


MMP-7 Overview

Name: MMP-7, MMP7, Matrix Metalloproteinase-7, MPSL1, PUMP-1, Matrilysin, Pump-1 Protease, PUMP-1, Uterine Metalloproteinase

Range: 1800-7.41 pg/ml

Species: Human

Sample Type: Serum, EDTA Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available

Analyte Description

Matrix metalloproteinase 7 (MMP7), also known as matrilysin, pump-1 protease (PUMP-1), or uterine metalloproteinase, is an enzyme that is involved with remodeling tissues. It is a member of the MMP family, a group of structural related zinc-dependent endopeptidases that are involved in breaking down different components of tissue. It is responsible for breaking down extracellular matrixes by degrading macromolecules such as casein, gelatins (type I, II, IV, andV), fibronectin, and proteoglycans. It also generates mature proteases which break down proteoglycans, fibronectin, elastin, and casein. It is critical during processes that require tissue changes, such as embryonic development, reproduction, wound healing, and tissue remodeling, but may also contribute to diseases such as arthritis and tumor metastasis. Upregulation of MMP7 is associated with tumor metastasis in many kinds of cancer, where it promotes the adhesion of cancer cells and facilitates their invasion into other tissues.

Q-Plex™ Products featuring MMP-7

Human Multiplex Kits

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