Human IL-17 Analyte Overview

Human IL-17

Also known as Interleukin-17, IL-17a

Interleukin 17 (IL-17) are a small family of similarly structured cytokines that plays a role in pro-inflammatory responses of the immune system, particularly allergic reactions. Each variant of IL-17 appears to have slightly nuanced function in different organs, but on the whole the cytokines behave similarly. IL-17 induces inflammation by stimulating the secretion of pro-inflammatory molecules such as IL-6, IL-8, GM-CSF, IL-1, TNF-α, and MCP-1 from their respective cell types. For this reason, IL-17 is linked to inflammatory and autoimmune diseases such as rheumatoid arthritis, asthma, lupus, psoriasis, and multiple scelrosis. Overactivity of IL-17 is commonly found in severe cases of asthma and psoriasis, where it contributes to inflammation that damages the airway and skin, respectively. IL-17 suppression is under investigation as a clinical target for reducing symptoms of inflammatory diseases, improving recovery following stroke, and treatment of some types of cancer.

IL-17 Q-Plex™ details

Species: Mouse
Assay Type: Sandwich
Sample Type: Serum
Assay Range: 10,000 – 13.72 pg/ml
Lower Limit of Detection (LLD): 6.20 pg/ml
Volume Required Per Well: Min 25µl
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate
Catalog No: 465349HU

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Measure IL-17 in 2.25 hours

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Sensitive, reproducible, and convenient 96-well format requiring low sample volumes

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Requires the Q-View™ Imaging System for analysis

Q-Plex Multiplexed Products featuring IL-17

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