sFAS

Analyte Overview

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sFAS

Name(s): sFAS, First Apoptosis Signal Receptor, Apoptosis Antigen 1, APO-1 APT, Tumor Necrosis Factor Receptor Superfamily Member 6, TNFRSF6

Ranges: 

        Human: 14600-20.03 pg/ml

Species: Human

Sample Type: Serum, EDTA Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available

 

Analyte Description

Soluble Fas (sFas) is a type I membrane protein that regulates apoptosis in the immune system. Fas receptor is expressed on the surface of activated lymphocytes and T cells and induces apoptosis when binding with Fas ligand. This process helps prevent an extended immune response and inflammation. sFas blocks this activity, preventing apoptosis. Elevated levels of sFas are implicated in a number of autoimmune diseases, including systemic lupus, diseases of blood stem cells, and chronic obstructive pulmonary disease. High levels of sFas are correlated with poor prognosis in patients with melanoma and other cancers.

Q-Plex™ Products featuring sFAS

Human Multiplex Kits

Current retail kits unavailable, contact an Account Executive for custom printing.

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