Human Chemokine (4-Plex)

Product at a Glance

Name: Q-Plex™ Human Chemokine (4-Plex)

Catalog: #125449HU

Kit Type: Multiplex ELISA

Multiplex Format: Antibody Array

Detection Method: Chemiluminescent

Analytes: IL-8, IP-10, MCP-1, Rantes

Product Overview

The Q-Plex™ Human Chemokine (4-Plex) is a fully quantitative ELISA-based chemiluminescent assay allowing concurrent measurement of four biomarkers or analytes (IL-8, IP-10, MCP-1, Rantes).

Each kit contains a 96-well plate, with each well featuring the relevant biomarker panel, and all the reagents required to perform testing. Q-Plex plates are built by absorbing four distinct capture antibodies in a defined array to the bottom of each well. Our high-quality reagents help ensure the accuracy of your results.

Using just 50 µl of sample per well, up to 80 samples can be assayed for all four markers in the panel in 2.5 hours. Q-Plex Arrays provide scientists with an easy-to-use and cost-effective means of generating a cytokine profile for each sample.

Kit Content

Each kit contains a 96-well plate, featuring the relevant biomarker panel in each well, and all reagents required to perform testing.

Reagents include:

  • Calibrator
  • Detection mix
  • Substrate
  • Sample diluents
  • Wash buffer
Assay Ranges
Units Calibrator Range LLD Limit
IL-8 pg/ml 2000 - 2.74 2.70
IP-10 pg/ml 4000 - 5.49 5.40
MCP-1 pg/ml 2000 - 2.74 2.60
Rantes pg/ml 7800 - 10.70 3.93

Positive Relationship between Total Antioxidant Status and Chemokines Observed in Adults

  • Authors: Yanli Li, Richard W. Browne, Matthew R. Bonner, et al.
  • Oxidative Medicine and Cellular Longevity Volume 2014 (2014).

Obstructive Sleep Apnea Is a Predictor of Abnormal Glucose Metabolism in Chronically Sleep Deprived Obese Adults

  • Authors: Cizza G, Piaggi P, Lucassen EA, de Jonge L, Walter M, et al.
  • Plos One 8 (May 29, 2013)

Pancreastatin-Dependent Inflammatory Signaling Mediates Obesity-Induced Insulin Resistance

  • Authors: Gautam K. Bandyopadhyay, Minh Lu, Ennio Avolio, et al.
  • Diabetes, 2015, doi: 10.2337/db13-1747
Assay Ranges
Units Calibrator Range LLD Limit
IL-8 pg/ml 2000 - 2.74 2.70
IP-10 pg/ml 4000 - 5.49 5.40
MCP-1 pg/ml 2000 - 2.74 2.60
Rantes pg/ml 7800 - 10.70 3.93

Positive Relationship between Total Antioxidant Status and Chemokines Observed in Adults

  • Authors: Yanli Li, Richard W. Browne, Matthew R. Bonner, et al.
  • Oxidative Medicine and Cellular Longevity Volume 2014 (2014).

Obstructive Sleep Apnea Is a Predictor of Abnormal Glucose Metabolism in Chronically Sleep Deprived Obese Adults

  • Authors: Cizza G, Piaggi P, Lucassen EA, de Jonge L, Walter M, et al.
  • Plos One 8 (May 29, 2013)

Pancreastatin-Dependent Inflammatory Signaling Mediates Obesity-Induced Insulin Resistance

  • Authors: Gautam K. Bandyopadhyay, Minh Lu, Ennio Avolio, et al.
  • Diabetes, 2015, doi: 10.2337/db13-1747