Analyte Overview



Name(s): CRP, C-reactive protein, PTX1, MGC149895, MGC88244


        Human: 50-0.07 ng/ml

Species: Human

Sample Type: Serum, Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available


Analyte Description

C-Reactive Protein (CRP) is a pentameric protein that functions as a sensor and activator for the innate immune system. It is secreted by the liver in response to immune factors released by macrophages and T cells, and rises in association with an inflammatory response. CRP binds to the surface of apoptotic cells and bacteria to activate the compliment system, which induces the phagocystosis and removal of dead or foreign cells. It also promotes dendritic cell maturation and humoral immunity. CRP is commonly measured as a marker of systemic inflammation. High levels are associated with cardiovascular disease, cancer, sleep apnea, and inflammatory diseases such as Crohn’s disease and inflammatory bowel disease (IBD). In cardiovascular disease, excess CRP binds to oxidized LDL cholesterol, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium.

Q-Plex™ Products featuring CRP

Human Multiplex Kits

As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.