Human HRP2 Analyte Overview
Also known as Plasmodium falciparum HRP2, Histidine rich protein 2
Histidine rich protein 2 (HRP2) is a protein consisting of over 70% histidine residues with unknown function. In Plasmodium falciparum it may play a role in binding or neutralizing heme in the cytoplasm of erythrocytes as well as suppressing the immune response through inhibition of IFNγ production. Notably, since HRP2 is an abundant blood-stage protein it has proven useful to develop antibodies against for detection of certain strains of Plasmodium.
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