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NHP CXCL-1 Analyte Overview

NHP CXCL-1

Also known as Chemokine Ligand 1, GROα, KC, CINC-1, Neutrophil-activating protein 3 (NAP-3), GRO1, Melanoma Growth Stimulating Activity alpha (MGSA-α)

CXCL-1 or GROα, is a proinflammatory chemokine that plays a role in immune responses and many cancers. In the healthy immune system, CXCL-1/GROα is produced by monocytes, epithelial cells, and fibroblasts in response to inflammatory activity. It induces neutrophil migration through chemotaxis and has antimicrobial effects. It is also capable of promoting lymphatic tube and blood vessel formation within the circulatory system. In individuals with chronic inflammatory diseases, it is produced at high levels by many cell types. Abnormally high levels of CXCL-1 stimulate the growth of tumors and are particularly associated with melanomas due to their normal expression in epithelial cells.

Typical Assay Characteristics

NHP CXCL-1 analyte graph
Precision Linearity
Inter-assay Intra-assay Range Average
8% 4% 73%-119% 94%

Q-Plex™ Details

Species: NHP
Assay Type: Sandwich
Sample Type: Serum/Plasma, Cell Supernatant
Assay Range: 2,000 – 2.74 pg/mL
Lower Limit of Detection (LLD): 1.37 pg/mL
Volume Required Per Well: Min. 25µL
Detection Method: Chemiluminescent
Singleplex Format: 96-well plate

Features & Requirements

  • Data available as fast as 4 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for analysis of multiplexed chemiluminescent planar-based arrays

Featured Q-Plex Products

Q-Plex™ NHP Chemokine Screen (9-Plex)

CXCL-1, IL-8, IP-10, MCP-1, MIF, MIG, MIP-1α, MIP-1ß, RANTES

Q-Plex™ NHP Cytokine Screen (16-Plex)

CXCL-1, GMCSF, IFNγ, IL-1ß, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-13, IL-15, IL-17A, IL-18, TNFα

Not Finding What You Need?

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Not seeing the biomarker or analyte you need? Customize your kit! The Q-Plex™ Custom Assays are fully quantitative ELISA-based Chemiluminescent assay kits allowing the concurrent measurement of up to 18 biomarkers or analytes.

Send in Your Samples

Choose up to 18 different biomarkers that will work best for your research. Send in your samples and let us run them for you. 

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Have questions about the kit or interested in more information? Contact one of our representative to get all your questions answered. 

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