NHP GMCSF Analyte Overview


Also known as granulocyte macrophage colony stimulating factor,  GM-CSF, colony-stimulating factor 2, CSF 2

Granulocyte-macrophage colony-stimulating factor (GM‑CSF), also known as colony-stimulating factor 2 (CSF2), is a growth factor that promotes the formation of white blood cells and is a critical component of the immune/inflammatory cascade. The growth factor is commonly used for in vitro colony formation of white blood cells. Numerous cell types produce GM-CSF in response to inflammation, particularly in the immune system, including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes. In hematopoietic cells, GM-CSF activates the functions of monocytes, macrophages, eosinophils, and granulocytes. In clinical settings, GM-CSF is capable of raising white blood cell counts in chemotherapy and bone marrow transplant patients and is being investigated as a potential cancer vaccination due to its ability to transfer targeted genetic material into tumor cells. Since GM-CSF initiates the development of an immune response, it is implicated in autoimmunity disorders and allergic inflammation.

Typical Assay Characteristics

NHP GMCSF analyte graph
Precision Linearity
Inter-assay Intra-assay Range Average
8% 8% 93%-178% 111%

Features & Requirements

  • Data available as fast as 4 hours
  • Sensitive, reproducible, and convenient 96-well format requiring low sample volumes
  • Requires the Q-View™ Imaging System for  analysis of multiplexed chemiluminescent planar-based arrays

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