NHP IL-15 Analyte Overview
Also known as Interleukin 15
Interleukin 15 (IL-15) is a common cytokine that is similar to IL-2 structurally and functionally and plays an important role in the innate immune system. IL-15 stimulates the proliferation of T-lymphocytes and natural killer cells, and assists in their maintenance, activation, and differentiation. Research on Interleukin 15 and its receptor complex indicate involvement in processes such as aging, cell maturation, and regulation of cellular processes. Overexpression of IL-15 is associated with pediatric asthma, Celiac disease, and non-alcoholic fatty liver disease, and anti-IL-15 therapeutics are under investigation for the treatment of these conditions. In cancer biology, IL-15 displays anti-tumor properties and is being reviewed as a component of both anti-viral and anti-tumor vaccines. IL-15 is a target of particular interest for patients with both HIV infection and cancer, as it appears to support improved both tumor reduction and improved immune function.
Typical Assay Characteristics
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