CD-14

Analyte Overview

\

CD-14

Name(s):  CD14, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, Cluster of differentiation 14

Ranges: 

        Human: 31700-43.48 pg/ml

Species: Human

Sample Type: Serum, Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available

 

Analyte Description

CD-14 is an acute phase glycoprotein that operates as a component of the innate immune system, where it is expressed primarily in the cell membranes of macrophages and neutrophils. It detects bacterial lipopolysaccharide, a component of the outer membrane of gram-negative bacteria. In the presence of lipopolysaccharide-binding protein, CD-14 binds with bacterial membranes to initiate a cascade response with TLR4 that triggers the activation of an inflammatory response. CD-14 may be either anchored to cell membranes or take a soluble form when excreted by liver cells and monocytes. Soluble CD-14 has the ability to confer the bacterial lipopolysaccharide response to cells that do not natively express CD-14 in their membranes and is found in human breastmilk, where it may act as a regulator of microbial growth in the infant gut.

Q-Plex™ Products featuring CD-14

Human Multiplex Kits

Current retail kits unavailable, contact an Account Manager for custom printing.

As researchers and problem solvers ourselves, we understand the value of sound data. We are proud to be a part of research that can better the world. We value the relationships, partnerships, and friendships that we have built with the people who trust and use our technology. We are committed to building these relationships. You can count on us to answer the phone and take time to thoroughly address questions or concerns about any of our products. In an industry that is reputed for grandiose claims, we trust that our quality standards and our customer service set us apart from the competition. If you’re happy with our products or if you think we can do something better, we hope you will let us know.

1-888-782-6797

info@quansysbio.com