IL-21

Analyte Overview

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IL-21 Overview

Name(s): IL-21, Interleukin 21

Ranges: 

      Human: 2000-2.74 pg/ml

Species: Human

Sample Type: Serum, EDTA Plasma

Detection: Chemiluminescent

Singleplex or Multiplex: Singleplex and Multiplex Available

 

Analyte Description

Interleukin 21 (IL-21) is a powerful cytokine that regulates the cells of both the innate and adaptive immune systems. In healthy individuals, IL-21 is produced by activated T cells, and it is also produced by cancerous cells in Hodgkin’s lymphoma. It is particularly influential on natural killer cells and cytotoxic T cells which work to eliminate infected and cancerous cells from the body. It also induces the proliferation of T cells, B cells, and natural killer cells. Dysregulation of IL-21 is often associated with immune-mediated diseases such as lupus, chronic inflammatory diseases, and psoriasis. Clinically, administration of IL-21 reduces the severity of allergic responses, encourages an anti-tumor immune response, and controls persistent viral infections. In patients with HIV, IL-21 inhibits viral reproduction and improves the function of other immune system components.

Q-Plex™ Products featuring IL-21

Human Multiplex Kits

Current retail kits unavailable, contact an Account Manager for custom printing.

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